Typhoid vaccine vs Antibiotics

Interacting Drugs
Typhoid vaccine
vs
Antibiotics
Security Level
Moderate, Consider therapy modification
Mechanism
Antibiotics: May diminish the therapeutic effect of Typhoid Vaccine. Only the live attenuated Ty21a strain is affected.
Management
Vaccination with live attenuated typhoid vaccine (Ty21a) should be avoided in patients being treated with systemic antibacterial agents. Use of this vaccine should be postponed until at least 24 hours after cessation of antibacterial agents. Exceptions: Acetic Acid; Aluminum Acetate; Azithromycin (Ophthalmic); Bacitracin; Benzoin; Capreomycin; Ciprofloxacin (Ophthalmic); Clindamycin (Topical); Dapsone (Topical); Erythromycin (Ophthalmic); Erythromycin (Topical); Fidaxomicin (Systemic); Gatifloxacin; Gentamicin (Ophthalmic); Gentamicin (Topical); Gentian Violet; Hexachlorophene; Mafenide; MetroNIDAZOLE (Topical); Neomycin; Oxychlorosene; Polymyxin B; Povidone-Iodine; Povidone-Iodine (Topical); Rifaximin; Silver Nitrate; Silver Sulfadiazine; Sulfacetamide (Ophthalmic); Sulfacetamide (Topical); Tobramycin (Ophthalmic).

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Other Interactions of Antibiotics

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