Pralatrexate vs Trimethoprim

Interacting Drugs
Pralatrexate
vs
Trimethoprim
Security Level
Minor, Monitor Therapy
Mechanism
Trimethoprim: May increase the serum concentration of PRALAtrexate. More specifically, trimethoprim may decrease excretion of pralatrexate.
Management
Closely monitor for increased pralatrexate serum level and/or possible toxicity with concomitant use of trimethoprim. Monitor for decreased pralatrexate levels with discontinuation of trimethoprim.

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Other Interactions of Pralatrexate

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Other Interactions of Trimethoprim

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