Pralatrexate vs Sulfamethoxazole

Interacting Drugs
Pralatrexate
vs
Sulfamethoxazole
Security Level
Minor, Monitor Therapy
Mechanism
Sulfamethoxazole: May increase the serum concentration of PRALAtrexate. More specifically, sulfamethoxazole may decrease excretion of pralatrexate.
Management
Closely monitor for increased pralatrexate serum level and/or possible toxicity with concomitant use of sulfamethoxazole. Monitor for decreased pralatrexate levels with discontinuation of sulfamethoxazole.

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Other Interactions of Pralatrexate

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Other Interactions of Sulfamethoxazole

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