Phenytoin vs Metyrapone

Interacting Drugs
Phenytoin
vs
Metyrapone
Security Level
Moderate, Consider therapy modification
Mechanism
Metyrapone: Phenytoin may decrease the serum concentration of Metyrapone. The oral metyrapone test would thus be unreliable unless the metapyrone dosage was substantially increased (e.g., 750 mg every 2 hours).
Management
Consider therapy modification

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Other Interactions of Phenytoin

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Other Interactions of Metyrapone

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