Phenytoin vs Lopinavir

Interacting Drugs
Phenytoin
vs
Lopinavir
Security Level
Moderate, Consider therapy modification
Mechanism
Lopinavir: Phenytoin may decrease the serum concentration of Lopinavir. Lopinavir may decrease the serum concentration of Phenytoin.
Management
The manufacturer of lopinavir/ritonavir recommends avoiding once-daily administration if used together with phenytoin.

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Other Interactions of Phenytoin

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Other Interactions of Lopinavir

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