Phenytoin vs Disulfiram

Interacting Drugs
Phenytoin
vs
Disulfiram
Security Level
Moderate, Consider therapy modification
Mechanism
Disulfiram: May increase the serum concentration of Phenytoin.
Management
Avoid concomitant use of disulfiram and phenytoin when possible. Phenytoin dose adjustment will likely be necessary when starting and/or stopping concurrent disulfiram. Monitor phenytoin response and concentrations closely.

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Other Interactions of Phenytoin

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Other Interactions of Disulfiram

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