Ofloxacin (systemic) vs Sulfonylureas

Interacting Drugs
Ofloxacin (systemic)
vs
Sulfonylureas
Security Level
Minor, Monitor Therapy
Mechanism
Sulfonylureas: Quinolone Antibiotics may enhance the hypoglycemic effect of Sulfonylureas. This appears to be particularly concerning early in the course of combination therapy. Quinolone Antibiotics may diminish the hypoglycemic effect of Sulfonylureas. With longer-term combination, there is a greater risk of hyperglycemia.
Management
Monitor therapy

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