Mephobarbital vs Teniposide

Interacting Drugs
Mephobarbital
vs
Teniposide
Security Level
Moderate, Consider therapy modification
Mechanism
Teniposide: Barbiturates may decrease the serum concentration of Teniposide.
Management
Consider alternatives to combined treatment with barbiturates and teniposide due to the potential for decreased teniposide concentrations. If the combination cannot be avoided, monitor teniposide response closely.

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