Lopinavir and ritonavir vs Codeine

Interacting Drugs
Lopinavir and ritonavir
vs
Codeine
Security Level
Moderate, Consider therapy modification
Mechanism
Codeine: CYP2D6 Inhibitors (Strong) may diminish the therapeutic effect of Codeine. These CYP2D6 inhibitors may prevent the metabolic conversion of codeine to its active metabolite morphine.
Management
Consider therapy modification

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Other Interactions of Lopinavir and ritonavir

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Other Interactions of Codeine

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