Ethinyl estradiol and etonogestrel vs Efavirenz

Interacting Drugs
Ethinyl estradiol and etonogestrel
vs
Efavirenz
Security Level
Moderate, Consider therapy modification
Mechanism
Efavirenz: May diminish the therapeutic effect of Etonogestrel.
Management
Use a reliable barrier contraceptive if efavirenz is used in combination with etonogestrel. Continue using barrier contraception for 12 weeks after discontinuation of efavirenz.

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