Interacting Drugs |
Ethacrynic acid vs Methotrexate |
Security Level |
|
Mechanism |
Methotrexate: May diminish the therapeutic effect of Loop Diuretics. Loop Diuretics may increase the serum concentration of Methotrexate. Methotrexate may increase the serum concentration of Loop Diuretics. |
Management |
Monitor for increased methotrexate and/or loop diuretic levels/toxicity with concomitant use of these agents and monitor for decreased therapeutic effects of loop diuretics. Methotrexate and/or loop diuretic dose reductions may be necessary. |
Ethacrynic acid vs Methotrexate
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Other Interactions of Ethacrynic acid
Other Interactions of Methotrexate
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