Duloxetine vs Tamoxifen

Interacting Drugs
Duloxetine

CYP2D6 Inhibitors


vs
Tamoxifen
Security Level
Moderate, Consider therapy modification
Interaction Effect

Duloxetine may decrease the effect of Tamoxifen.

Mechanism

CYP2D6 Inhibitors (Moderate) may decrease the metabolism of Tamoxifen. Specifically, CYP2D6 inhibitors may decrease the formation of highly potent active metabolites.

Management

Consider alternatives with less of an inhibitory effect on CYP2D6 activity when possible.


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Duloxetine vs Tamoxifen

Interacting Drugs
Duloxetine
vs
Tamoxifen
Security Level
Moderate, Consider therapy modification
Mechanism
Tamoxifen: CYP2D6 Inhibitors (Moderate) may decrease the metabolism of Tamoxifen. Specifically, CYP2D6 inhibitors may decrease the formation of highly potent active metabolites.
Management
Consider alternatives with less of an inhibitory effect on CYP2D6 activity when possible.

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Subscribe to our e-mail newsletter to receive updates.

No comments yet.

Post Review about Duloxetine vs Tamoxifen