Disulfiram vs Ritonavir

Interacting Drugs
Disulfiram
vs
Ritonavir
Security Level
Major, Avoid combination
Mechanism
Ritonavir: Disulfiram may enhance the adverse/toxic effect of Ritonavir. This is specific for the lopinavir/ritonavir (Kaletra) oral solution due to its alcohol content (42%).
Management
Concomitant use of Kaletra (lopinavir/ritonavir) oral solution and disulfiram should be avoided. Kaletra contains 42% alcohol.

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Other Interactions of Ritonavir

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