Didanosine vs Tenofovir

Interacting Drugs
Didanosine
vs
Tenofovir
Security Level
Major, Avoid combination
Mechanism
Tenofovir: May diminish the therapeutic effect of Didanosine. Tenofovir may increase the serum concentration of Didanosine.
Management
Avoid concomitant treatment with tenofovir and didanosine. Consider altering even existing, stable treatment to avoid this combination.

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