Desipramine vs Alpha2-Agonists

Interacting Drugs
Desipramine
vs
Alpha2-Agonists
Security Level
Moderate, Consider therapy modification
Mechanism
Alpha2-Agonists: Tricyclic Antidepressants may diminish the antihypertensive effect of Alpha2-Agonists. Exceptions: Apraclonidine; Brimonidine.
Management
Consider therapy modification

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