Cyproterone and ethinyl estradiol vs Fosaprepitant

Interacting Drugs
Cyproterone and ethinyl estradiol
vs
Fosaprepitant
Security Level
Moderate, Consider therapy modification
Mechanism
Fosaprepitant: May decrease the serum concentration of Contraceptives (Estrogens). The active metabolite aprepitant is likely responsible for this effect.
Management
Alternative or additional methods of contraception should be used both during treatment with fosaprepitant or aprepitant and for at least one month following the last fosaprepitant/aprepitant dose.

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