Buprenorphine and naloxone vs Atazanavir

Interacting Drugs
Buprenorphine and naloxone
vs
Atazanavir
Security Level
Major, Avoid combination
Mechanism
Atazanavir: Buprenorphine may decrease the serum concentration of Atazanavir. Atazanavir may increase the serum concentration of Buprenorphine.
Management
Avoid this combination in patients un-boosted atazanavir due to possible decreased atazanavir concentrations. This combination is not contraindicated in patients also receiving ritonavir, but monitoring for buprenorphine toxicity is recommended.

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Other Interactions of Atazanavir

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