Bicalutamide vs Eplerenone

Interacting Drugs
Bicalutamide
vs
Eplerenone
Security Level
Moderate, Consider therapy modification
Mechanism
Eplerenone: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Eplerenone.
Management
A lower starting dose of eplerenone (25 mg once daily for adults) is recommended in patients with hypertension who are also taking drugs that are moderate inhibitors of CYP3A4.

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