Atorvastatin vs Gemfibrozil

Interacting Drugs
Atorvastatin
vs
Gemfibrozil
Security Level
Moderate, Consider therapy modification
Mechanism
Gemfibrozil: May enhance the myopathic (rhabdomyolysis) effect of Atorvastatin. Gemfibrozil may increase the serum concentration of Atorvastatin.
Management
To minimize the risk of toxicity consider using micronized fenofibrate instead of gemfibrozil. Gemfibrozil should only be considered in patients receiving lower atorvastatin doses. Monitor patients closely for signs/symptoms of muscle toxicity.

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Other Interactions of Atorvastatin

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Other Interactions of Gemfibrozil

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