Flupirtine

Flupirtine is used as an analgesic for acute and chronic pain, in moderate to severe cases.
As a muscle relaxant used for back pain.
It is also used for migraines.

Future possibilities : Flupirtine has been noted for its neuro-protective properties, and it is being investigated for possible use in Creutzfeld-Jakob disease, Alzheimer's disease, fibromyalgia and multiple sclerosis.It has also been proposed as a possible treatment for Batten disease.

Established hypersensitivity to flupirtine.
Flupirtine should not be given to patients at risk of a hepatic encephalopathy nor to patients suffering from cholestasis, since an encephalopathy or ataxia may develop or deteriorate.
As flupirtine loosens muscle tenseness patients suffering from myasthenia gravis should not be treated with flupirtine.
Since flupirtine is mostly metabolized in the liver, patients with a liver disease and alcohol abusers should not be given Flupirtine. 

liver toxicity and rare cardiac effects related to its mechanism of action in patients predisposed to cardiac disease.

Dizziness, heartburn, nausea / vomiting, gastric disorders, constipation, disturbed sleep, outbreak of sweat, lack of appetite, depression, tremor, headache, abdominal pain, dryness of the mouth, restlessness / nervousness, flatulence, diarrhoea,Confusion, visual disturbances and allergic reactions, in isolated cases with a raised body temperature, manifested themselves in symptoms such as rash, urticaria and itching. 

Flupirtine may interact with anticoagulants such as warfarin. A blood test called the PT is needed to monitor this potential interaction. Alcohol or other sedatives such as benzodiazepines can increase the tiredness and dizziness that you may experience with flupirtine.

Flupirtine is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.

N: FDA has not classified this drug.

Not Known