Indications |
Intravenous Acute oesophageal variceal haemorrhage Adult: Initially, 2 mg followed by 1 or 2 mg every 4-6 hr until bleeding is controlled, for up to 72 hr. |
Contraindications |
Hypersensitivity, vascular disease esp coronary artery disease, chronic nephritis (until normal blood-nitrogen conc attained). Pregnancy. |
Warnings / Precautions |
Patients with hypertension, artherosclerosis, cardiac disorders, conditions which may be aggravated by water retention, eg. heart failure. |
Adverse Reactions |
Abdominal cramps, cardiac arrhythmias, headache, transient blanching, increased arterial pressure. Potentially Fatal: MI, cardiac failure. |
Mechanism of Actions |
Terlipressin, a synthetic triglycyl-lysine derivative of vasopressin, is a inactive prodrug. It has pressor and antidiuretic effects. Following IV injection, lysine vasopressin are released following the enzymatic cleavage of 3 glycyl moieties. Duration: 4-6 hr. |
Storage Conditions |
Intravenous: Store below 25°C. |
ATC Classification |
H01BA04 - terlipressin ; Belongs to the class of vasopressin and analogues. Used in posterior pituitary lobe hormone preparations. |
Storage |
Intravenous: Store below 25°C. |
Available As |
|
Terlipressin
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Terlipressin Containing Brands
Terlipressin is used in following diseases
Drug - Drug Interactions of Terlipressin
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