Vulvovaginal candidiasis
Adult: 40 mg (as 0.8% vag cream) or 80 mg (as pessary) at bedtime for 3 consecutive nights or 20 mg (as 0.4% cream) at bedtime for 7 consecutive nights.
Hypersensitivity. Lactation.
Warnings / Precautions
Discontinue if irritation or flu-like symptoms develop. May damage latex or rubber contraceptives. Patients <18 yrs. Pregnancy.
Adverse Reactions
Vulvovaginal burning, vulvar itching, dysmenorrhoea, genital, body and abdominal pain. Flu-like syndrome with headache, fever, chills and hypotension with doses >80 mg.
Mechanism of Actions
Terconazole disrupts ergosterol synthesis by binding to fungal cytochrome P450. It is active in vitro against Candida spp and other fungi. It has some antibacterial activity in vitro but not against usual vag flora eg, lactobacilli.
Absorption: Intravaginal: 5-16% absorbed
Metabolism: Hepatic metabolism
Excretion: Excreted in urine and faeces.
Storage Conditions
Vaginal: Store between 15-30°C.
ATC Classification
G01AG02 - terconazole ; Belongs to the class of triazole derivative antiinfectives. Used in the treatment of gynecological infections.
Vaginal: Store between 15-30°C.
Available As
  • Terconazole 0.8% w/w
  • Terconazole 80 mg
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