Indications |
Special Populations: Reduce dose in renal impairment. |
Contraindications |
Sensitivity to sulfonamides, severe renal or hepatic impairment, porphyria, SLE; infants <2 mth; pregnancy (3rd trimester), lactation. |
Warnings / Precautions |
Renal insufficiency, elderly, blood dyscrasias, G6PD deficiency, AIDS. |
Adverse Reactions |
Nausea, vomitting, diarrhoea, hypersensitivity skin reaction, hypothyroidism, crystalluria, renal impairment , blood dyscrasias, kernicterus in premature neonates. Potentially Fatal: Stevens-Johnson syndrome, agranulocytosis and aplastic anaemia. |
Drug Interactions |
Concurrent use may increase phenytoin and methotrexate levels; increased risk of bleeding with warfarin and acenocoumarol; may potentiates antidiabetic effect of sulfonylureas. Potentially Fatal: Increased risk of blood dyscrasias with clozapine and pyrimethamine. See Below for More sulfamoxole Drug Interactions |
Lab Interactions |
Interference with tests for urea, creatinine, urinary glucose, urobilinogen. |
Mechanism of Actions |
Sulfamoxole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid. |
ATC Classification |
J01EC03 - sulfamoxole ; Belongs to the class of intermediate-acting sulfonamides. Used in the systemic treatment of infections. |
Available As |
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Sulfamoxole
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Sulfamoxole Containing Brands
Sulfamoxole is used in following diseases
Drug - Drug Interactions of Sulfamoxole
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