Special Populations: Reduce dose in renal impairment.
Sensitivity to sulfonamides, severe renal or hepatic impairment, porphyria, SLE; infants <2 mth; pregnancy (3rd trimester), lactation.
Warnings / Precautions
Renal insufficiency, elderly, blood dyscrasias, G6PD deficiency, AIDS.
Adverse Reactions
Nausea, vomitting, diarrhoea, hypersensitivity skin reaction, hypothyroidism, crystalluria, renal impairment , blood dyscrasias, kernicterus in premature neonates.
Potentially Fatal: Stevens-Johnson syndrome, agranulocytosis and aplastic anaemia.
Drug Interactions
Concurrent use may increase phenytoin and methotrexate levels; increased risk of bleeding with warfarin and acenocoumarol; may potentiates antidiabetic effect of sulfonylureas.
Potentially Fatal: Increased risk of blood dyscrasias with clozapine and pyrimethamine.
See Below for More sulfamoxole Drug Interactions
Lab Interactions
Interference with tests for urea, creatinine, urinary glucose, urobilinogen.
Mechanism of Actions
Sulfamoxole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.
ATC Classification
J01EC03 - sulfamoxole ; Belongs to the class of intermediate-acting sulfonamides. Used in the systemic treatment of infections.
Available As
  • Sulfamoxole 100 mg
  • Sulfamoxole 400 mg
  • Sulfamoxole 500 mg
  • Sulfamoxole 800 mg
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