Somatostatin

Indications	Intravenous Gastrointestinal haemorrhage *Adult:* Initially, 250 mcg as a bolus inj over 3-5 min, followed by a continuous infusion of 3.5 mcg/kg/hr until bleeding has ceased. May continue for a further 48-72 hr to prevent recurrent bleeding.
Warnings / Precautions	Monitor blood glucose levels. May inhibit intestinal absorption thus concomitant parenteral nutrition may be recommended.
Adverse Reactions	Rapid infusion may lead to abdominal discomfort, nausea, flushing, bradycardia.
Mechanism of Actions	Somatostatin is a polypetide obtained synthetically or from the hypothalamus. It acts by inhibiting the release of growth hormone from the anterior pituitary. It also inhibits the release of thyrotrophin and corticotropin from the pituitary, glucagon and insulin from the pancreas. It also regulates duodenal and gastric secretions. It may also play a role in pain perception.
ATC Classification	H01CB01 - somatostatin ; Belongs to the class of antigrowth hormone. Used in hypothalamic hormone preparations.
Available As	Somatostatin 0.25 mg Somatostatin 3 mg

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Somatostatin Containing Brands

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Somatostatin is used in following diseases

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Drug - Drug Interactions of Somatostatin

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