Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Child: 10 mg/kg as a single dose.
Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Adult: 10 mg/kg daily for 5 days.
Warnings / Precautions
Liver dysfunction, anaemia or severe malnutrition. Treat members in close contact with the patient.
Adverse Reactions
Anorexia, nausea, vomiting, abdominal cramps, drowsiness, insomnia, diarrhoea, tenesmus, SGOT elevations, headache, dizziness, rash.
Drug Interactions
Potentially Fatal: Mutually antagonistic with piperazine.
See Below for More pyrantel Drug Interactions
Mechanism of Actions
Pyrantel is effective against roundworms (Ascaris), threadworms (Enterobius), hookworms and Trichostrongylus. Not effective against whipworm. Acts by paralysing the worms which get detached and are excreted by intestinal peristalsis.
Absorption: Minimally absorbed from the GI tract (oral).
Excretion: Via urine (7% as unchanged drug and metabolites), via faeces (>50% as unchanged).
May be taken with or without food.
ATC Classification
P02CC01 - pyrantel ; Belongs to the class of tetrahydropyrimidine derivative agents. Used as antinematodal.
Available As
  • Pyrantal Pamoate 100 mg
  • Pyrantel Pamoate 100 mg
  • Pyrantel 125 mg
  • Pyrantel 200 mg
  • Pyrantel Pamoate 25 mg
  • Pyrantel Pamoate 250 mg
  • Pyrantal Pamoate 250 mg
  • Pyrantel 250 mg
  • Pyrantel Pamoate 50 mg
  • Pyrantel 50 mg
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