Pertussis Vaccine

Indications
 Intramuscular
Active immunisation against pertussis
Adult: 11-64 yr: As combination product with diphtheria and tetanus toxoids: 0.5 ml as a single dose, preferably into the deltoid muscles. Ensure that 5 yr should have elapsed since the last dose of tetanus toxoid, diphtheria toxoid and/or pertussis containing vaccine.
Child: As a combination product with diphtheria, tetanus, inactivated poliomyelitis and HIB conjugate vaccine: 3 doses of 0.5 ml each, given at 1 mth intervals. Booster dose may be given at 18 mth-6 yr of age prior to school entry (3 yr after primary course).
Contraindications
 Hypersensitivity to active substances and/or neomycin, polymyxin or formaldehyde.
Warnings / Precautions
 Continue immunisation with acellular pertussis vaccine even during episodes of fever, hypotonic-hyporesponsive episodes, persistent crying or screaming or severe local reactions have occurred after a preceding dose. Children with personal or family history of convulsions or epilepsy. Children with a local or general reaction to a whole-cell pertussis vaccine should complete their immunisation with acellular pertussis vaccine. If a seizure associated with fever occurs within 72 hr of immunisation or a child experiences encephalopathy or encephalitis within 7 days of immunisation, defer further immunisation until the condition is stable if no underlying cause is found and the child has not recovered completely within 24 hr.
Adverse Reactions
 Local reactions at inj site, fever and irritability, may start a few hrs after inj and last for 1 or 2 days, possibly with inflammation and lymphangitis. Rare neurological reactions e.g. convulsions and encephalopathy. Hypersensitivity reactions may occur and anaphylaxis has been reported rarely.
Drug Interactions
 Reduced immune response in patients who are also taking immunosuppressants.
See Below for More vaccine, pertussis Drug Interactions
Mechanism of Actions
 Pertussis vaccine is used for active immunisation against pertussis.
Storage Conditions
 Intramuscular: Store at 2-8 °C, do not freeze and protect from light.
Storage
 Intramuscular: Store at 2-8 °C, do not freeze and protect from light.
Available As
  • Pertussis Vaccine
  • Pertussis Vaccine –
  • Pertussis Vaccine 12 oz
  • Pertussis Vaccine 160
  • Pertussis Vaccine 160 u
  • Pertussis Vaccine 20000 iu
  • Pertussis Vaccine 4 iu
  • Pertussis Vaccine 40000 iu
  • Pertussis Vaccine 8 mcg

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    Pertussis Vaccine Containing Brands

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    Pertussis Vaccine is used in following diseases

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    Drug - Drug Interactions of Pertussis Vaccine

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