Nystatin

Indications
 Oral
Intestinal or oropharyngeal candidiasis
Adult: 500,000 or 1,000,000 units 3-4 times daily.
Child: As oral suspension: 100,000 units 4 times daily.
Oral
Oral candidiasis
Adult: As pastilles or oral suspension; 100,000 units 4 times daily (US recommendation 200,000-400,000 units as lozenges or 400,000-600,000 units as oral suspension 4 times daily). Keep in contact with affected area for as long as possible. Avoid food and drink for 1 hr after dose. Continue for 48 hr after lesions have healed.
Child: >1 mth: As pastilles or oral suspension; 100,000 units 4 times daily (US recommendation 200,000-400,000 units as lozenges or 400,000-600,000 units as oral suspension 4 times daily). Keep in contact with affected area for as long as possible. Avoid food and drink for 1 hr after dose. Continue for 48 hr after lesions have healed.
Oral
Prophylaxis of intestinal candidiasis
Adult: 1,000,000 units daily in divided doses.
Child: Infants, as oral suspension: 100,000 units daily.
Vaginal
Vaginal candidiasis
Adult: 100,000-200,000 units daily for 14 days as pessaries or vaginal cream.
Topical/Cutaneous
Cutaneous or mucocutaneous mycotic infections
Adult: As ointment, gel, cream, or dusting powder containing 100,000 units/g: apply 2-4 times daily.
Child: As ointment, gel, cream, or dusting powder containing 100,000 units/g: apply 2-4 times daily.
Contraindications
 Hypersensitivity.
Warnings / Precautions
 Pregnancy, lactation.
Adverse Reactions
 Diarrhoea, GI distress, nausea and vomiting. vaginal pessaries/cream: May damage latex contraceptives (e.g. diaphragms, condoms), additional contraceptive measures should be taken. Topical application: Irritation.
Food Interactions
 Oral suspension/drops: Reduced efficacy if food/drink taken within 1 hr of drug admin.
Mechanism of Actions
 Nystatin, a polyene antifungal, binds to ergosterol in the fungal cell membrane. This binding affects the cell wall permeability allowing leakage of cellular contents.
Administration
 May be taken with or without food.
Storage Conditions
 Oral: Store at 15-30°C. Topical/Cutaneous: Store at 15-30°C. Vaginal: Store at room temperature.
ATC Classification
 D01AA01 - nystatin ; Belongs to the class of antibiotics. Used in the topical treatment of fungal infection.
G01AA01 - nystatin ; Belongs to the class of antibiotics. Used in the treatment of gynecological infections.
A07AA02 - nystatin ; Belongs to the class of antibiotics. Used in the treatment of intestinal infections.
Storage
 Oral: Store at 15-30°C. Topical/Cutaneous: Store at 15-30°C. Vaginal: Store at room temperature.
Available As
  • Nystatin 1,00,000 iu
  • Nystatin 1,00,000 units
  • Nystatin 100 units
  • Nystatin 100000 iu
  • Nystatin 100000 units
  • Nystatin 5,00,000 units

    • Subscribe for latest updates

    Subscribe to our e-mail newsletter to receive updates.

    No comments yet.

    Post Review about Nystatin


    Nystatin Containing Brands

    We are Developing Our database, More results coming soon.

    Nystatin is used in following diseases

    We are Developing Our database, More results coming soon.

    Drug - Drug Interactions of Nystatin

    We are Developing Our database, More results coming soon.