Niclosamide

Indications	Oral Pork tapeworm infestation *Adult:* 2 g as a single dose after a light breakfast. *Child:* <2 yr: 500 mg; 2-6 yr: 1 g. All doses to be taken as a single dose after a light breakfast. Oral Beef or fish tapeworm infections *Adult:* 1 g after breakfast and 1 g an hr later. *Child:* <2 yr: 250 mg after breakfast and 250 mg an hr later; 2-6 yr: 500 mg after breakfast and 500 mg an hr later. Oral Dwarf-tapeworm infections *Adult:* Initially, 2 g on the 1st day followed by 1 g daily for 6 days. *Child:* <2 yr: 500 mg on the 1st day followed by 250 mg daily for 6 days; 2-6 yr: 1 g on the 1st day followed by 500 mg daily for 6 days.
Contraindications	Hypersensitivity.
Adverse Reactions	GI disturbances (e.g. nausea, retching, abdominal pain), lightheadedness, pruritus.
Drug Interactions	Possible increase in adverse effects with alcohol. See Below for More niclosamide Drug Interactions
Mechanism of Actions	Niclosamide is active against intestinal tapeworms. It inhibits oxidative phosphorylation in mitochondria of the worms resulting in energy depletion. Absorption: Insignificantly absorbed from the GI tract (oral).
Administration	Should be taken with food. (Take after meals.)
Storage Conditions	Oral: Store below 25°C.
ATC Classification	P02DA01 - niclosamide ; Belongs to the class of salicylic acid derivative agents. Used as anticestodals.
Storage	Oral: Store below 25°C.
Available As	Niclosamide 1000 mg Niclosamide 500 mg

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