Adult: 0.5 mg daily when used alone or 0.75-2.5 mg daily when used in combination with an oestrogen.
Menstrual disorders
Adult: 5-10 mg daily as cyclic regimen.
Undiagnosed vaginal bleeding, active venous thromboembolic disorders or severe arterial disease, hepatic impairment, progestogen-dependent tumours, porphyria. Pregnancy.
Warnings / Precautions
CV or renal dysfunction, hypertension, epilepsy, migraine, asthma, DM, conditions which may be exacerbated by fluid retention, malabsorption syndrome, post ectopic pregnancy, functional ovarian cysts, thromboembolism. Lactation.
Adverse Reactions
GI disturbances, changes in appetite or weight, fluid retention, oedema, rashes, urticaria, mental depression, breast tenderness and pain, gynaecomastia, changes in libido, headache, migraine, altered menstrual cycle, irregular menstrual bleeding, changes in LFTs and serum lipid profile.
Potentially Fatal: Anaphylaxis or anaphylactoid reactions.
Drug Interactions
Increased metabolism and subsequent reduction in efficacy with enzyme-inducing agents e.g. carbamazepine, griseofulvin, phenobarbital, phenytoin and rifampicin. Adjustment in antidiabetic dose may be required.
Potentially Fatal: May increase plasma levels and toxicity of ciclosporin.
See Below for More lynestrenol Drug Interactions
Mechanism of Actions
Lynestrenol is a progestogen structurally related to norethisterone. It may be used alone or as the progestogenic component of some oral contraceptives.
May be taken with or without food.
ATC Classification
G03AC02 - lynestrenol ; Belongs to the class of progestogens. Used as systemic contraceptives.
G03DC03 - lynestrenol ; Belongs to the class of estren derivative progestogens used in progestogenic hormone preparations.
Available As
  • Lynestrenol 1 mg
  • Lynestrenol 2.5 mg
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