Lornoxicam

Indications
 Oral
Pain relief
Adult: 8-16 mg daily. Max: 24 mg daily.
Oral
Osteoarthritis
Adult: 12 mg daily in 2-3 divided doses, up to 16 mg daily if needed.
Oral
Rheumatoid arthritis
Adult: 12 mg daily in 2-3 divided doses, up to 16 mg daily if needed.
Parenteral
Pain relief
Adult: 8 mg once or twice daily by IM/IV inj. Max: 24 mg daily.

Special Populations: Reduce dose in elderly.
Contraindications
 Patients with peptic ulceration; severe renal impairment; pregnancy and lactation.
Warnings / Precautions
 Active infections; asthma; allergic disorders; haemorrhagic disorders; hypertension; impaired renal, hepatic, cardiac function.
Adverse Reactions
 Abdominal pain, diarrhoea, dizziness, dyspepsia, nausea, vomiting; headache; haematologic disorders; CNS effects; visual disturbance; tinnitus; nephrotoxicity; fluid retention; photosensitivity; alveolitis; pancreatitis; Stevens-Johnson syndrome; toxic epidermal necrolysis; colitis induction/exacerbation; stomatitis; hypertension, palpitation; insomnia, somnolence.
Drug Interactions
 Increased lornoxicam blood conc when given concomitantly with cimetidine.Enhanced effects of anticoagulants, sulfonylureas, methotrexate, ciclosporin, digoxin. Decreased effects of diuretics, ACE inhibitors.
Potentially Fatal: Increased risk of lithium toxicity.
See Below for More lornoxicam Drug Interactions
Mechanism of Actions
 Lornoxicam is an NSAID that is used in musculoskeletal, joint disorders and other painful conditions including postoperative pain. Lornoxicam is a potent inhibitor of both COX-1 and COX-2 enzymes.
Absorption: Extensively absorbed from the GI tract. Peak plasma concentration within 1-2 hr (oral) or 25 min (IM).
Distribution: 99% bound to plasma proteins.
Metabolism: Metabolised to its inactive metabolite.
Excretion: Excreted in the faeces (as metabolites) and urine (as unchanged drug). Mean elimination half life of 3-4 hr.
ATC Classification
 M01AC05 - lornoxicam ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, oxicams.
Available As
  • Lornoxicam 16 mg
  • Lornoxicam 4 mg
  • Lornoxicam 8 mg

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    Lornoxicam Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Tablet Algesin (4 mg) Alembic Chemical Works Co Ltd 1 Tablet
    ₹ 3.50    		 10 Tablet
    ₹ 35.00
  • More Information Lornoxicam 4 mg
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    Tablet Axilocam (4 mg) Axis Life Science Pvt Ltd 1 Tablet
    ₹ 3.50    		 100 Tablet
    ₹ 350.00
  • More Information Lornoxicam 4 mg
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    Tablet Lornasafe (8 mg) Mankind Pharmaceuticals Pvt. Ltd. 1 Tablet
    ₹ 2.99    		 10 Tablet
    ₹ 29.90
  • More Information Lornoxicam 8 mg
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    Tablet Lornicam (4 mg) Aristo Pharmaceuticals Pvt Ltd. 1 Tablet
    ₹ 2.00    		 10 Tablet
    ₹ 19.95
  • More Information Lornoxicam 4 mg
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    Tablet Lornicam Plus (4+500) Aristo Pharmaceuticals Pvt Ltd. 1 Tablet
    ₹ 2.90    		 10 Tablet
    ₹ 29.00
  • More Information Paracetamol 500 mg
  • More Information Lornoxicam 4 mg
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    Tablet Lorniflex (4 mg) Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.) 1 Tablet
    ₹ 2.00    		 10 Tablet
    ₹ 19.95
  • More Information Lornoxicam 4 mg
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    Tablet Lorniflex Plus (4+500) Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.) 1 Tablet
    ₹ 2.90    		 10 Tablet
    ₹ 29.00
  • More Information Paracetamol 500 mg
  • More Information Lornoxicam 4 mg
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    Tablet Lornoxi (4 mg) Kris (Hetero Healthcare Ltd) 1 Tablet
    ₹ 1.90    		 10 Tablet
    ₹ 19.00
  • More Information Lornoxicam 4 mg
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    Tablet Loxcam (8 mg) Akesiss Pharma Pvt Ltd 1 Tablet
    ₹ 2.90    		 10 Tablet
    ₹ 29.00
  • More Information Lornoxicam 8 mg
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    Tablet Mitilor FC (4 mg) Spectra (FDC Limited) 1 Tablet
    ₹ 2.90    		 10 Tablet
    ₹ 29.00
  • More Information Lornoxicam 4 mg
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