Gastro-oesophageal reflux disease, Irritable bowel syndrome, Dyspepsia
Adult: 25 mg tid.
Elderly: Dose reductions may be necessary.

Special Populations: Lower initial doses have been recommended in elderly patients, subsequently adjusted as required. Dosage adjustment is also advised in patients with renal impairment.
Phaeochromocytoma, epilepsy, manic states, hyperprolactinaemia, mammary dysplasia, malignant mastopathies, cardiac impairment. GI bleeding, mechanical obstruction or perforation.
Warnings / Precautions
May impair ability to drive or operate machinery. Pregnancy and lactation.
Adverse Reactions
Amenorrhoea, gynaecomastia, galactorrhoea, changes in libido.
Potentially Fatal: Neuroleptic malignant syndrome.
Drug Interactions
Reduced bioavailability with sucralfate, aluminium- and magnesium-containing antacids. Effect on GI motility may be antagonised by anticholinergic agents, narcotics and analgesics. Avoid alcohol.
See Below for More levosulpiride Drug Interactions
Mechanism of Actions
Levosulpiride is a substituted benzamide, which exerts antidopaminergic (selective dopamine D2 receptors) activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent.
Absorption: Oral bioavailability is about 30%; peak plasma concentrations after about 3 hr.
Excretion: Mainly via urine. Plasma half-life: 9.7 hr (oral); 4.3 hr (IV).
Storage Conditions
Oral: Store at 15-30°C (59-86°F).
ATC Classification
N05AL07 - levosulpiride ; Belongs to the class of benzamides antipsychotics.
Oral: Store at 15-30°C (59-86°F).
Available As
  • Levosulpiride 100 mg
  • Sulpiride (Levosulpiride) 100 mg
  • Levosulpiride 12.5 mg
  • Sulpiride (Levosulpiride) 200 mg
  • Levosulpiride 25 mg
  • Sulpiride (Levosulpiride) 400 mg
  • Levosulpiride 50 mg
  • Levosulpiride 75 mg
  • Subscribe for latest updates

    Subscribe to our e-mail newsletter to receive updates.

    One Response to Levosulpiride

    1. sandeep gurjar March 28, 2013 at 11:45 am #

      i have completed m.pharma project on LEVOSULPIRIDE 75mg(sustain release tablets) .that reduse tid 25mg that admistrade only one time 75mg so is best reduse side effect…….

      sandeep gurjar
      v.po tilawali teh. khetri jhunjhunu(rajasthan)

    Post Review about Levosulpiride

    Levosulpiride Containing Brands

    We are Developing Our database, More results coming soon.

    Levosulpiride is used in following diseases

    We are Developing Our database, More results coming soon.

    Drug - Drug Interactions of Levosulpiride

    We are Developing Our database, More results coming soon.