Hydrogen Peroxide

Indications
 Mouth/Throat
Acute stomatitis
Adult: 1.5% solution used as a mouthwash or as a deodorant gargle.
Otic/Aural
Removal of earwax
Adult: Dilute 6% hydrogen peroxide solution with 3 parts of water, immediately before use.
Topical/Cutaneous
Wound cleansing
Adult: 6% solution or 1-1.5% cream.
Contraindications
 Inj or instillation of hydrogen peroxide into closed body cavities.
Adverse Reactions
 Irritating burns on the skin and mucous membranes (strong solutions); reversible hypertrophy of the papillae of the tongue with continued use as mouthwash; gas embolism, rupture of the colon, proctitis, ulcerative colitis and gangrene of the intestines have occurred following colonic lavage with hydrogen peroxide solution.
Mechanism of Actions
 Hydrogen peroxide is an oxidising agent with antibacterial and antiviral activity. It is used as an antiseptic, disinfectant, and deodorant. It also has a mild haemostatic action. It exerts its antiseptic action partly by its ready release of oxygen when applied to tissues, but this effect is reduced in the presence of organic matter. The mechanical effect of effervescence may be more useful for wound cleansing than the antimicrobial action.
Storage Conditions
 Mouth/Throat: Store at 15-30°C. Otic/Aural: Store at 15-30°C. Topical/Cutaneous: Store at 15-30°C.
ATC Classification
 A01AB02 - hydrogen peroxide ; Belongs to the class of local antiinfective and antiseptic preparations. Used in the treatment of diseases of the mouth.
D08AX01 - hydrogen peroxide ; Belongs to the class of other antiseptics and disinfectants. Used in the treatment of dermatological diseases.
S02AA06 - hydrogen peroxide ; Belongs to the class of antiinfectives used in the treatment of ear infections.
Storage
 Mouth/Throat: Store at 15-30°C. Otic/Aural: Store at 15-30°C. Topical/Cutaneous: Store at 15-30°C.
Available As
  • Hydrogen Peroxide 0.6%
  • Hydrogen Peroxide 1.5%
  • Hydrogen Peroxide 1.5% w/v
  • Hydrogen Peroxide 6% w/v

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