Gramicidin

Indications
 Ophthalmic
Ocular infections
Adult: Instill 1-2 drops or apply ointment 2-4 times daily, usually in combination with other antibacterials (eg, neomycin and polymyxin B) and frequently with a corticosteroid.
Topical/Cutaneous
Superficial infections
Adult: Apply thinly bid-tid.
Contraindications
 Porphyria.
Adverse Reactions
 Local sensitivity reactions, Stevens-Johnson syndrome.
Potentially Fatal: Liver and kidney damage.
Mechanism of Actions
 Gramicidin is an antibacterial which is too toxic to be used systemically, so it is rather used as a topical and ophth agent and in combination with other antibacterials (neomycin and polymixin B) and also with corticosteroids.
ATC Classification
 R02AB30 - gramicidin ; Belongs to the class of antibiotics used in throat preparations.
Available As
  • Gramicidin 0.025 gm
  • Gramicidin 0.025 mg
  • Gramicidin 0.025% w/w
  • Gramicidin 0.25 mg
  • Gramicidin 25 iu

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