Fosfestrol

Indications	Oral Malignant neoplasms of the prostate *Adult:* As Na: 360-480 mg tid. Maintenance: 120-240 mg tid; may gradually reduce to 240 mg daily. Intravenous Malignant neoplasms of the prostate *Adult:* As Na: Initially, 600-1200 mg daily by slow IV Inj for 5-10 days followed by 300 mg daily for 10-20 days. Maintenance: 300-600 mg, reduce slowly over few mth from dosing 4 times/wk to once wkly.
Contraindications	Pregnancy. Hypersensitivity.
Warnings / Precautions	Cardiovascular disease, hepatic impairment. Slow infusion is not recommended.
Adverse Reactions	Nausea, fluid retention, arterial and venous thrombosis, impotence, gynecomastia, withdrawal bleeding, hypercalcaemia, bone pain.
ATC Classification	L02AA04 - fosfestrol ; Belongs to the class of estrogens.
Available As	Fosfestrol 120 mg Fosfestrol 60 mg

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