Prophylaxis of migraine, Prophylaxis of vertigo and vestibular disorders, Prophylaxis of peripheral and cerebrovascular disorders
Adult: 5-10 mg daily at bedtime.
Pregnancy, lactation, GI or urinary tract obstruction, acute porphyrias.
Warnings / Precautions
Driving or operating machinery, epilepsy, elderly, CVS disease, glaucoma.
Adverse Reactions
Drowsiness. Rarely wt gain, headache, depression, gastric pain, dry mouth, insomnia, extrapyramidal reactions, galactorrhoea.
Drug Interactions
Plasma levels reduced by phenytoin, carbamazepine, valproic acid.
See Below for More flunarizine Drug Interactions
Mechanism of Actions
Flunarizine has H1-receptor blocking action and calcium-channel blocking effect. It has also been used as an adjunct epileptic therapy for patients refractory to standard treatment regimens.
Absorption: Absorbed well from the GI tract (oral).
Distribution: Highly lipophilic. Protein-binding: >90%.
Metabolism: Extensive.
Excretion: Via bile (as metabolites); 18 days (elimination half-life).
May be taken with or without food.
Storage Conditions
Oral: Store below 25°C.
ATC Classification
N07CA03 - flunarizine ; Belongs to the class of antivertigo preparations.
Oral: Store below 25°C.
Available As
  • Flunarizine 10 mg
  • Flunarizine Hcl 10 mg
  • Flunarizine 5 mg
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