Etizolam

Indications
 Oral
Short-term management of anxiety, Insomnia
Adult: Up to 3 mg daily in divided doses or as a single dose at night.
Contraindications
 Acute narrow-angle glaucoma; myasthenia gravis; resp depression; coma; acute pulmonary insufficiency; sleep apnoea syndrome; severe hepatic impairment. Chronic psychosis. Phobic or obsessional states; may precipitate suicide or aggressive behavior, not to be used alone to treat depression or anxiety associated with depression. Porphyria. Pregnancy and lactation. Neonates.
Warnings / Precautions
 Chronic pulmonary insufficiency, muscle weakness, impaired liver or kidney function, or in patients with history of alcohol or drug addiction. Elderly or debilitated patients. May affect performance of skilled tasks. Patients with personality disorders or organic brain changes. Hypotension occasionally occur with high dosage. Dependence.
Adverse Reactions
 Drowsiness, sedation, muscle weakness and ataxia. Less frequently, vertigo, headache, confusion, depression, slurred speech or dysarthria, changes in libido, tremor, visual disturbances, urinary retention or incontinence, GI disturbances, changes in salivation and amnesia.
Drug Interactions
 Enhanced sedation or respiratory and CV depression with drugs with CNS depressant properties e.g., antidepressants, antihistamines, antipsychotics, general anaesthetics, other hypnotics or sedatives, opioid analgesics and cisapride. Calcium-channel blockers; clonidine; diazoxide; disulfiram; clozapine; diuretics; moxonidine; nabitone; nitrates; cimetidine, esomeprazole and omeprazole; muscle relaxants; dopaminergics; lofexidine; hydralazine, minoxidil and nitroprusside; antifungals; angiotensin II receptor antagonist; antiepileptics; β-blockers; antibacterials. Alcohol.
See Below for More etizolam Drug Interactions
Mechanism of Actions
 Etizolam is a derivative of benzodiazepine that is used for the short-term treatment of insomnia and anxiety disorder. It has the same general properties with that of diazepam.
ATC Classification
 N05BA19 - etizolam ; Belongs to the class of benzodiazepine derivatives anxiolytics. Used in the management of anxiety, agitation or tension.
Available As
  • Etizolam 0.25 mg
  • Etizolam 0.5 mg
  • Etizolam 1 mg

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