Indications |
Oral Hypersensitivity reactions Adult: 25 mg every 4-6 hr. Max: 150 mg daily. Child: Oral Insomnia Adult: 25 mg given 30 minutes before retiring at night. |
Contraindications |
Severe liver disease; avoid alcohol; premature infants or full-term neonates. |
Warnings / Precautions |
May impair ability to drive and operate machinery. Angle-closure galucoma, urinary retention, prostatic hypertrophy or pyloroduodenal obstruction; epilepsy; hepatic impairment. Elderly. Lactation. |
Adverse Reactions |
Acute dystonic reactions and long-lasting impaired consciousness in child. CNS depression including slight drowsiness to deep sleep, lassitude, dizziness, incoordination. Headache, psychomotor impairment and antimuscarinic effects. Rarely rashes and hypersensitivity reactions, blood disorders, convulsions, sweating, myalgia, extrapyramidal effects, tremor, confusion, tinnitus, hypotension, hair loss. |
Drug Interactions |
Enhance effects of CNS depressants eg alcohol, barbiturates, hypnotics, opioid analgesics, anxiolytic sedatives and antipsychotics. Atropine, TCAs, MAOIs. Can mask signs of ototoxicity caused by aminoglycosides. See Below for More doxylamine Drug Interactions |
Mechanism of Actions |
Doxylamine is an antihistamine derived from monoethanolamine possessing antimuscarinic and pronounced sedative effects. Absorption: Plasma concentrations peak 2-3 hr after oral admin. |
Administration |
Should be taken with food. (Take w/ food or milk.) |
Storage Conditions |
Oral: Store at 15-30°C. |
ATC Classification |
R06AA09 - doxylamine ; Belongs to the class of aminoalkyl ethers used as systemic antihistamines. |
Storage |
Oral: Store at 15-30°C. |
Available As |
|
Doxylamine
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Doxylamine Containing Brands
Doxylamine is used in following diseases
Drug - Drug Interactions of Doxylamine
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