Dipivefrine Hydrochloride

Indications	Ophthalmic Ocular hypertension, Open-angle glaucoma *Adult:* As hydrochloride: Instil 1 drop of 0.1% soln in the eye/s every 12 hr.
Contraindications	Hypersensitivity. Patients with narrow angles, since any pupillary dilatation may cause an attack of angle-closure glaucoma.
Warnings / Precautions	Aphakic patients; lactation.
Adverse Reactions	Ocular hyperaemia, burning, stinging, irritation, follicular conjunctivitis, mydriasis, allergic reactions, adrenochrome deposits in the conjunctiva and cornea, headache, browache and eye pain. Very rarely, tachycardia and hypertension may occur. Potentially Fatal: Generally well tolerated. Side effects fewer when compared to epinephrine drops.
Drug Interactions	Additive ocular hypotensive effects with other anti-glaucoma drugs. See Below for More dipivefrine Drug Interactions
Mechanism of Actions	Dipivefrine is a prodrug of adrenaline. It reduces IOP by decreasing aqueous production and by enhancing outflow.
ATC Classification	S01EA02 - dipivefrine ; Belongs to the class of sympathomimetics used in the treatment of glaucoma.
Available As	Dipivefrine Hydrochloride 0.1%

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Drug - Drug Interactions of Dipivefrine Hydrochloride

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