Indications |
Oral Intestinal amoebiasis Adult: 500 mg tid for 10 days. May repeat course if needed. Child: >25 kg: 20 mg/kg daily in 3 divided doses for 10 days, repeated if necessary. |
Warnings / Precautions |
Pregnancy and lactation. |
Adverse Reactions |
Flatulence, anorexia, nausea, vomiting, pruritus, urticaria. |
Mechanism of Actions |
Diloxanide is a luminal amoebicide which is hydrolysed in the gut, thus releasing the free diloxanide which acts as an amoebicide. It is given alone in asymptomatic cyst passers. For patients with active amoebic infections, it can be administered with a 5-nitroimidazole e.g. metronidazole or tinidazole. Absorption: Absorbed from the GI tract (oral). Metabolism: Rapidly hydrolysed prior to absorption. Excretion: Via faeces (<10% of dose). |
Storage Conditions |
Oral: Store at 25°C. |
ATC Classification |
P01AC01 - diloxanide ; Belongs to the class of dichloroacetamide derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases. |
Storage |
Oral: Store at 25°C. |
Available As |
|
Diloxanide
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Diloxanide Containing Brands
Diloxanide is used in following diseases
Drug - Drug Interactions of Diloxanide
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