Desonide

Indications
 Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As 0.05% cream, ointment or lotion: Apply sparingly onto the affected areas 2-4 times/day. Discontinue therapy when control is achieved.
Contraindications
 Hypersensitivity to any of the components. Primary infective skin conditions.
Warnings / Precautions
 Caution when using in paed patients. Evaluate periodically for evidence of HPA-axis suppression. In the event of secondary infections use appropriate antibiotics and discontinue topical steroid. Pregnancy and lactation.
Adverse Reactions
 Burning, itching, irritation, scaling, folliculitis, hypertrichosis, contact dermatitis, skin peeling, transient erythema.
Overdose Reactions
 Systemic absorption of topical corticosteroids can result in reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome, hyperglycemia and glucosuria. Glucocorticosteroid insufficiency may occur upon withdrawal of treatment. If HPA axis suppression is present, withdraw drug or reduce the frequency of application. Alternatively, a less potent corticosteroid may be used instead. Recovery of HPA axis function is generally prompt upon discontinuation of topical corticosteroids. Supplemental systemic corticosteroids may be needed in the treatment of glucocorticosteroid insufficiency.
Mechanism of Actions
 Desonide is a corticosteroid used mainly for its glucocorticoid activity in the treatment of various skin disorders.
Storage Conditions
 Topical/Cutaneous: Store below 30°C.
ATC Classification
 D07AB08 - desonide ; Belongs to the class of moderately potent (group II) corticosteroids. Used in the treatment of dermatological diseases.
S01BA11 - desonide ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
Storage
 Topical/Cutaneous: Store below 30°C.
Available As
  • Desonide 0.05% w/w

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