Adult: 10-40 mg daily or on alternate days, reduce frequency for maintenance.
Adult: 5-10 mg daily alone or in conjunction with other antihypertensives.
Severe hepatic or renal impairment; anuria; Addison's disease; hypercalcaemia.
Warnings / Precautions
Fluid and electrolyte disturbances; hepatic cirrhosis; gout; diabetes mellitus. Elderly; severe heart failure; renal or hepatic impairment. Monitor blood glucose concentrations in patients taking antidiabetics. Pregnancy and lactation.
Adverse Reactions
Electrolyte imbalance; hyperglycaemia; gout; dry mouth; thirst; weakness; muscle pain and cramp; seizures; hypotension; GI disturbances; anorexia; sialadenitis; headache; impotence; yellow vision; hypersensitivity reactions; cholestatic jaundice; pancreatitis; blood dyscrasias; glycosuria; dizziness; photosensitivity reactions, postural hypotension, paraesthesia.
Drug Interactions
Digitalis glycosides; drugs that prolong QT interval; other antihypertensives; competitive muscle relaxants; pressor amines; corticosteroids, corticotrophin; β2-agonists, α-blockers; ACE inhibitors; NSAIDs; alcohol, barbiturates; opioids; lithium; allopurinol; tetracyclines; carbenoxolone; hypoglycaemics.
See Below for More clopamide Drug Interactions
Mechanism of Actions
Clopamide reduces the reabsorption of electrolytes from the renal tubules, hence increasing the excretion of Na and chloride ions and consequently of water. It also reduces the glomerular filtration rate.
Onset: 1-2 hrs.
Duration: Up to 24 hrs.
Storage Conditions
Oral: Store below 30°C.
ATC Classification
C03BA03 - clopamide ; Belongs to the class of low-ceiling sulfonamide diuretics.
Oral: Store below 30°C.
Available As
  • Clopamide 20 mg
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