Clioquinol

Indications
 Topical/Cutaneous
Skin fungal infections
Adult: Apply 3% cream or ointment 2-4 times daily onto affected areas (cleansed and dried thoroughly). Treatment continued for 4 wk for athlete's foot or ringworm and for 2 wk when treating jock itch.
Contraindications
 Hypersensitivity; child <2 yr. Do not apply on eczematous or broken skin and perforated tympanic membrane.
Warnings / Precautions
 Can stain fabric and skin. Avoid contact with eyes; avoid prolonged use. Not effective in the treatment of fungal infections of the scalp or nails. Discontinue if local irritation, rash, sensitivity occur.
Adverse Reactions
 Severe irritation or hypersensitivity. Cross-sensitivity with other halogenated hydroxyquinolines. May discolour fair hair.
Potentially Fatal: May cause severe neurotoxicity.
Mechanism of Actions
 Clioquinol is a halogenated hydroxyquinoline with antibacterial and antifungal activity.
ATC Classification
 D08AH30 - clioquinol ; Belongs to the class of quinolone derivative antiseptics. Used in the treatment of dermatological diseases.
D09AA10 - clioquinol ; Belongs to the class of ointment dressings with antiinfectives.
G01AC02 - clioquinol ; Belongs to the class of quinolone derivative antiinfectives. Used in the treatment of gynecological infections.
P01AA02 - clioquinol ; Belongs to the class of hydroxyquinoline derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.
S02AA05 - clioquinol ; Belongs to the class of antiinfectives used in the treatment of ear infections.
Available As
  • Clioquinol 3%
  • Clioquinol 3% w/v
  • Clioquinol 3% w/w
  • Clioquinol 8%

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