Benzoyl peroxide

Indications
 Topical/Cutaneous
Acne
Adult: Apply a 2.5-10% preparation once or twice daily, often used with other antimicrobials.
Topical/Cutaneous
Decubitus/stasis ulcers
Adult: Apply a 20% lotion every 8-12 hr.
Contraindications
 Hypersensitivity.
Warnings / Precautions
 Discontinue if severe irritation develops. Restart with tolerable levels of treatment after irritiation has cleared. Do not use occlusive dressing. May cause dermatitis in allergic patients. Apply carefully near the eyes, mouth, neck and other mucous membranes as well as other sensitive areas.
Adverse Reactions
 Excessive drying of skin, allergic dermatitis. May bleach fabrics or hair. Skin discoloration; skin rash, peeling, transient local oedema.
Drug Interactions
 PABA sunscreens may transiently discolour fabric.
See Below for More benzoyl peroxide Drug Interactions
Mechanism of Actions
 Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.
Metabolism: Skin; converted to benzoic acid.
Excretion: Urine.
Storage Conditions
 Topical/Cutaneous: Store at 15-30°C.
ATC Classification
 D10AE01 - benzoyl peroxide ; Belongs to the class of topical peroxide preparations used in the treatment of acne.
Storage
 Topical/Cutaneous: Store at 15-30°C.
Available As
  • Benzoyl peroxide 1% w/w
  • Benzoyl peroxide 10% w/w
  • Benzoyl peroxide 2.5 mg
  • Benzoyl peroxide 2.5%
  • Benzoyl peroxide 2.5% w/w
  • Benzoyl peroxide 4%
  • Benzoyl peroxide 4% w/w
  • Benzoyl peroxide 5 mg
  • Benzoyl peroxide 5%
  • Benzoyl peroxide 5% w/w

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