Ardeparin

Indications
Subcutaneous
Prophylaxis of deep vein thrombosis
Adult: Initially 50 iu/kg following surgery. Subsequently, 50 iu/kg bid for 14 days after surgery or until ambulatory.
Contraindications
Hypersensitivity, thrombocytopaenia, active major bleeding, active peptic ulcer.
Warnings / Precautions
Renal or hepatic impairment, history of GI ulceration, uncontrolled hypertension, spinal or epidural anaesthesia. Pregnancy, lactation; elderly. Periodic blood counts, including platelet count and stool occult blood test recommended.
Adverse Reactions
Thrombocytopaenia, mild bleeding, Inj site irritation, pain and ecchymoses, hypersensitivity and erythema.
Potentially Fatal: Haemorrhagic complications.
Drug Interactions
Potentially Fatal: Risk of haemorrhage increased with oral anticoagulants, platelet aggregation inhibitors, NSAIDs including aspirin.
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Mechanism of Actions
Ardeparin Na is a LMWH with anticoagulant activity. It has been used for the prevention of post-op venous thromboembolism.
Excretion: Elimination half-life: 3.5 hr.
Available As
  • Ardeparin 2500 iu
  • Ardeparin 5000 iu
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