Amorolfine (Amorolfin)

Indications	Topical/Cutaneous Nail fungal infections *Adult:* As 5% nail lacquer. Apply onto infected fingernails or toenails once or twice wkly after filing and cleansing, allow to dry. Continue until nail is regenerated and affected areas cured. Usual treatment duration: 6 mth (fingernails) and 9-12 mth (toenails). Topical/Cutaneous Skin fungal infections *Adult:* As 0.25% cream. Apply once daily in the evening after cleansing for at least 2-3 wk (up to 6 wk for foot infections). Continue for 3-5 days after cure is attained.
Contraindications	Hypersensitvity.
Warnings / Precautions	Avoid contact with eyes, mucous membranes and ears. Pregnancy, lactation.
Adverse Reactions	Skin irritation with erythema and pruritus; slight transient burning sensation (rare); hypersensitivity reactions.
Mechanism of Actions	Amorolfine acts by interfering with synthesis of sterols required for functioning of fungal cell membranes. It is active in vitro against a wide variety of pathogenic and opportunistic fungi and possesses variable activity against Aspergillus spp.
Storage Conditions	Topical/Cutaneous: Store below 30°C.
ATC Classification	D01AE16 - amorolfine ; Belongs to the class of other antifungals for topical use.
Storage	Topical/Cutaneous: Store below 30°C.
Available As	Amorolfine (Amorolfin) 5% Amorolfine (Amorolfin) 5% w/v

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