Temazepam vs OLANZapine

Interacting Drugs
Temazepam
vs
OLANZapine
Security Level
Major, Avoid combination
Mechanism
OLANZapine: May enhance the adverse/toxic effect of Benzodiazepines.
Management
Avoid concomitant use of parenteral benzodiazepines and IM olanzapine due to risks of additive adverse events (e.g., cardiorespiratory depression). Olanzapine prescribing information provides no specific recommendations regarding oral administration.

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