Pegylated interferon (peginterferon) alfa-2a and ribavirin vs Reverse Transcriptase Inhibitors (Nucleoside)

Interacting Drugs
Pegylated interferon (peginterferon) alfa-2a and ribavirin
vs
Reverse Transcriptase Inhibitors (Nucleoside)
Mechanism
Reverse Transcriptase Inhibitors (Nucleoside): Ribavirin may enhance the hepatotoxic effect of Reverse Transcriptase Inhibitors (Nucleoside). Lactic acidosis may occur.
Management
Consider therapy modification

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Interaction
Major, Avoid combination Rilpivirine vs Reverse Transcriptase Inhibitors (Non-Nucleoside)
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Moderate, Consider therapy modification Pegylated interferon (peginterferon) alfa-2b and ribavirin vs Reverse Transcriptase Inhibitors (Nucleoside)
Minor, Monitor Therapy Paclitaxel vs Reverse Transcriptase Inhibitors (Non-Nucleoside)
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