Ofloxacin (systemic) vs Theophylline Derivatives

Interacting Drugs
Ofloxacin (systemic)
vs
Theophylline Derivatives
Security Level
Moderate, Consider therapy modification
Mechanism
Theophylline Derivatives: Quinolone Antibiotics may decrease the metabolism of Theophylline Derivatives. Ciprofloxacin and enoxacin are of greatest concern. Theophylline/quinolone therapy might augment the seizure-producing potential of each of the individual agents. Exceptions: Dyphylline.
Management
Consider therapy modification

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