Lansoprazole, amoxicillin, and clarithromycin vs Tacrolimus

Interacting Drugs
Lansoprazole, amoxicillin, and clarithromycin
vs
Tacrolimus
Security Level
Minor, Monitor Therapy
Mechanism
Tacrolimus: Macrolide Antibiotics may increase the serum concentration of Tacrolimus.
Management
Monitor therapy

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Post Review about Lansoprazole, amoxicillin, and clarithromycin vs Tacrolimus

Lansoprazole, amoxicillin, and clarithromycin vs Tacrolimus

Interacting Drugs
Lansoprazole, amoxicillin, and clarithromycin
vs
Tacrolimus
Security Level
Moderate, Consider therapy modification
Mechanism
Tacrolimus: Proton Pump Inhibitors may increase the serum concentration of Tacrolimus.
Management
Tacrolimus dose adjustment may be required. Rabeprazole, pantoprazole, or selected H2-receptor antagonists (i.e., ranitidine or famotidine) may be less likely to interact. Genetic testing may predict patients at highest risk.

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Post Review about Lansoprazole, amoxicillin, and clarithromycin vs Tacrolimus