Haloperidol vs Anti-Parkinson’s Agents (Dopamine Agonist)

Interacting Drugs
Haloperidol
vs
Anti-Parkinson's Agents (Dopamine Agonist)
Security Level
Moderate, Consider therapy modification
Mechanism
Anti-Parkinson's Agents (Dopamine Agonist): May diminish the therapeutic effect of Antipsychotics (Typical). Antipsychotics (Typical) may enhance the therapeutic effect of Anti-Parkinson's Agents (Dopamine Agonist).
Management
Avoid concomitant therapy if possible and monitor for decreased effects of both agents when these combinations cannot be avoided. Atypical antipsychotics such as clozapine and quetiapine may be less likely to reduce the effects of anti-Parkinson's agents.

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